Bio-processing Simulations
Bio-processing is the industry that use living cell to produce useful products. Much like chemical processing, the goal is to product as much product as efficiently as possible. Computational fluid dynamics is used widely in the chemical processing industry for both upstream and downstream applications. We at Singularity Engineering brings these same techniques to help the bio-process industry.
Scale up
Scale up of a bio-process can be very expensive and time consuming. We help companies avoid trial and error by optimizing the scale up process in simulation.
Mixing simulation
The starting point of scale up is to ensure proper mixing. Mix too fast the large fluid dynamics shear can kill organism. Too slow and the air and nutrients can concentrate and cause poor growth.
Mixing simulation is a quick and efficient way to take some of the guess work out up scale up.
Mixing with Acidity
Microbes of all types need just the right environment to thrive. PH is a key factor that need to be controlled.
By including the PH control into a mixing simulation gives more insight into what will help the targeted organism thrive.
PH control
Oxygen concentration
Multiphase and reactions
Adding spargers, gas bubbles and reactions allows fluid dynamics simulations to predict oxygen distribution and mass transfer. This provides valuable insight into the effectiveness of the bio-reactor
Mixing optimization
Why do 1 simulation when you can automatically run through many possibilities.
Fluid dynamics simulations allows bio-process engineers to identify the optimal operating conditions in a fraction of the time it takes to run 1 experiment.
Down Stream
Filtration
Products from a bio-reactor must be harvested. This typically involves some filtration process. Simulation an enhance the yield of this process for both mixing tanks and continuous process systems.
separation
Bio-processing generates valuable products. These must be separate from waste. The creation of an efficient separation system can result in huge increases in yield. Simulations have been used extensively to improve and optimize separation equipment as well as operating conditions.
Spray simulation
Nozzle design for sprays can be tricky. Performance depends heavily on viscosity, pressure and velocity of the flow. However spray drying can be a essential step in down-stream processing.
With our advanced fluid dynamics simulations, we can model spry nozzle and spray performance. This allows process engineers to further optimize their downstream process without costly and time consuming prototyping and testing.
Spray simulation
This is a few examples of the work we do for the bio-process industry. Singularity Engineering uniquely provides a mixture of consulting, training and software license to ensure we meet the need of every customer. If you’ve read this far, please reach out to us using the Contact Us button below.
We are committed to your success.